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Popular Article
Probiotics: The Futuristic Alternative of Antibiotics?
Suryasarathi Kumar*, Ankita Pan, Isha Dey and Sneha Sarkar
Abstract
Probiotics are a natural alternative to antibiotics and are generally used to treat microbial infections that cause a variety of human and animal ailments. Doctors often prescribe antibiotics to treat diseases caused by microbial systems, such as bacteria or fungi. However, their excessive and improper usage has contributed to the rise in antimicrobial resistance, dysbiosis, or imbalance of the host microbiota despite antibiotics being the most well-known life-saving drugs. Antimicrobial resistance among microorganisms has emerged as a significant danger to global health, potentially resulting in millions of deaths annually in the past and future. It is imperative that antibiotic alternatives can be found and developed in light of these global problems because there is some evidence that probiotics can fight infections, control immunological responses, and maintain overall host health by re-establishing the balance of the gut microbiota. Probiotics can act as antibiotics if the gut microflora is identified and treated with plant extracts that solely stimulate these probiotic bacteria. If the treated bacteria exhibit more efficacy than the untreated bacteria, recombinant DNA technology can increase its effectiveness; as a result, it can be a more effective substitute for such high-dose antibiotics. The present study thoroughly explains the antimicrobial resistance problems associated with antibiotic use and the possibility of using probiotics as antibiotic alternatives.
Keywords
Probiotics, antibiotics, antimicrobial resistance, biotechnological strategies
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Miao, V., Coëffet-LeGal, M.-F., Brian, P., Brost, R., Penn, J., Whiting, A., Martin, S., Ford, R., Parr, I., Bouchard, M., Silva, C. J., Wrigley, S. K., & Baltz, R. H. (2005). Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry. Microbiology (Reading, England), 151(Pt 5), 1507–1523. https://doi.org/10.1099/mic.0.27757-0
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Petersen, C., & Round, J. L. (2014). Defining dysbiosis and its influence on host immunity and disease: How changes in microbiota structure influence health. Cellular Microbiology, 16(7), 1024–1033. https://doi.org/10.1111/cmi.12308
Pissowotzki, K., Mansouri, K., &Piepersberg, W. (1991). Genetics of streptomycin production in Streptomyces griseus: molecular structure and putative function of genes strELMB2N. Molecular & General Genetics: MGG, 231(1), 113–123. https://doi.org/10.1007/bf00293829
Raheem, A., Liang, L., Zhang, G., & Cui, S. (2021). Modulatory effects of probiotics during pathogenic infections with emphasis on immune regulation. Frontiers in Immunology, 12, 616713. https://doi.org/10.3389/fimmu.2021.616713
- Published online
- 19th February, 2024
How to Cite the Article
Kumar, S., Pan, A., Dey, I. and Sarkar, S. 2024. Probiotics: The Futuristic Alternative of Antibiotics? Chronicle of Aquatic Science 1(9): 15-21.
Copyright
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
CoAS_V1IS9_02
