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Mini-review
Genotoxicity Unveiled: A Minireview of Mechanisms, Detection, and Implications
Gowhar Iqbal*, Shafiya Mushtaq, Ad Viral Kumar Ganpatbhai, Lukram Sushil Singh and Sangeetha S
 
Abstract
The term "genotoxicity" is defined as the presence of a substance that has a detrimental effect on the genetic material (DNA, RNA) of the cell, hence impairing the integrity of the cell. Mutagens called genotoxins can potentially damage DNA or chromosomal material, resulting in a mutation. Genotoxins are substances that can harm DNA or chromosomal structure, resulting in mutations. It can be radiation or chemicals. Regulatory agencies worldwide demand data on the new drug’s potential to cause genotoxicity as part of the safety evaluation process. While the damage to the germ cell will result in heritable disorders, the damage to the somatic cells will result in various diseases, including cancer. Regulatory agencies worldwide demand data on the new drug’s potential to cause genotoxicity as part of the safety evaluation process.
 
Keywords
Genotoxicity, DNA Damage, Genotoxins, Cancer, Genotoxicity Assay
 
References
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How to Cite the Article
Iqbal et al., (2023) Genotoxicity Unveiled: A Minireview of Mechanisms, Detection, and Implications. Chronicle of Aquatic Science 1(2): 44-50
 
Copyright
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. 
 
 

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